Senior Scientist, Analytical R&D

Merck is seeking a Senior Scientist, Analytical R&D to lead late‑stage method development and validation for large‑molecule vaccines and biologics in South San Francisco, San Mateo County, USA.

Key Responsibilities

• Oversee late‑stage analytical method development, qualification, and validation for Phase III through product launch.
• Design and execute robust analytical strategies for large‑molecule pipelines and existing biologic products.
• Collaborate with manufacturing, regulatory, and supply‑chain teams to ensure seamless technology transfer.
• Lead troubleshooting and root‑cause investigations for analytical issues.
• Mentor junior scientists and contribute to continuous improvement initiatives.

Required Qualifications

• Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or related field.
• 8+ years of experience in analytical development of biologics, vaccines, or large‑molecule therapeutics.
• Strong expertise in chromatography, spectroscopy, mass spectrometry, and bio‑analytical techniques.
• Proven track record of method validation and regulatory filing support (FDA/EMA).
• Excellent communication, project‑management, and cross‑functional collaboration skills.

What We Offer

• Competitive salary of $159,392.05 annually.
• Comprehensive benefits package and professional development opportunities.
• Dynamic, fast‑paced environment within a global leader in healthcare.

Frequently Asked Questions

What type of products will I work on as a Senior Scientist at Merck?

You will focus on large‑molecule therapeutics, including vaccines and biologics, from late‑stage development through launch.

What qualifications are required for this position?

A Ph.D. in a relevant scientific discipline and at least 8 years of analytical development experience with biologics.

What is the salary for this role?

The position offers a fixed annual salary of $159,392.05.