Director/Senior Director, Clinical Operations

Protego Biopharma, Inc. is seeking a Director or Senior Director of Clinical Operations to lead the execution of early‑stage clinical programs in San Diego, San Diego County. This senior role offers a fixed annual salary of $324,340.90.

Key Responsibilities

• Design, implement, and oversee clinical trial strategies for first‑in‑class small‑molecule therapeutics targeting protein‑folding diseases.
• Lead cross‑functional teams including clinical research, regulatory, data management, and biostatistics to ensure milestones are met on time and within budget.
• Develop and maintain relationships with CROs, academic sites, and key opinion leaders.
• Ensure compliance with FDA regulations, ICH guidelines, and GCP standards.
• Prepare and present clinical development updates to senior leadership and investors.
• Drive risk‑based monitoring plans and continuous improvement of operational processes.

Required Qualifications

• Advanced degree (PhD, MD, PharmD, or equivalent) with extensive experience in clinical operations for biotech or pharmaceutical companies.
• 10+ years of progressive responsibility, including at least 5 years in a director‑level role overseeing Phase I‑III trials.
• Proven track record of delivering complex programs on schedule and within budget.
• Strong knowledge of regulatory requirements (FDA, EMA, ICH) and clinical trial management systems.
• Excellent leadership, communication, and stakeholder management skills.

What We Offer

• Competitive fixed salary of $324,340.90 per year.
• Opportunity to shape innovative therapies for rare and degenerative diseases.
• Collaborative, science‑driven environment in a leading biotech hub.

Frequently Asked Questions

What therapeutic areas will I work on in this role?

You will lead clinical programs focused on protein misfolding diseases, including myopathy, cardiomyopathy, stroke, renal and retinal diseases, channelopathies, and other degenerative conditions.

Is prior experience with CRO management required?

Yes, experience managing CRO relationships and overseeing outsourced trial activities is essential for success in this position.

What is the salary structure for this position?

The role offers a fixed annual salary of $324,340.90 with no additional variable components listed.